Rabbit Secondary Antibodies
Creative Diagnostics Rabbit Anti-Human ErbB3 monoclonal antibody, clone TQ82, 100UL
ERBB3; erb-b2 receptor tyrosine kinase 3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3
Jackson Immuno Research Labs Fluorescein (FITC)-AffiniPure Rabbit Anti-Human IgG (H+L)
Fluorescein (FITC)-AffiniPure Rabbit Anti-Human IgG (H+L)
ABclonal Technology 594 Rabbit anti-Human AXL
The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal followed by two fibronectin type-III motifs It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6) This gene may be involved in several cellular functions including growth migration aggregation and anti-inflammation in multiple cell types The encoded protein acts as a host cell receptor for multiple viruses including Marburg Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus
Jackson Immuno Research Labs Alexa Fluor 647 AffiniPure Rabbit Anti-Human IgG, Fcγ fragment specific, 1mg
Alexa Fluor 647 AffiniPure Rabbit Anti-Human IgG, Fcγ fragment specific, 1mg
ABclonal Technology 594 Rabbit anti-Human FATP1
Enables biotin transmembrane transporter activity efflux transmembrane transporter activity and long-chain fatty acid transporter activity Involved in several processes including carboxylic acid transmembrane transport glycerophospholipid biosynthetic process and lipid transport across blood-brain barrier Located in membrane Part of plasma membrane
ABclonal Technology 647 Rabbit anti-Human CD45
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitosis and oncogenic transformation This PTP contains an extracellular domain a single transmembrane segment and two tandem intracytoplasmic catalytic domains and thus is classified as a receptor type PTP This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling It functions through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling This PTP also suppresses JAK kinases and thus functions as a regulator of cytokine receptor signaling Alternatively spliced transcripts variants of this gene which encode distinct isoforms have been reported
Jackson Immuno Research Labs AMCA-AffiniPure Rabbit Anti-Human IgG (H+L)
AMCA-AffiniPure Rabbit Anti-Human IgG (H+L)
ABclonal Technology 488 Rabbit anti-Human CD161
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation Several genes of the C-type lectin superfamily including the rodent NKRP1 family of glycoproteins are expressed by NK cells and may be involved in the regulation of NK cell function The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins a transmembrane domain and a cytoplasmic domain The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus
ABclonal Technology PE Rabbit anti-Human CD86 mAb
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily This protein is expressed by antigen-presenting cells and it is the ligand for two proteins at the cell surface of T cells CD28 antigen and cytotoxic T-lymphocyte-associated protein 4 Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response Alternative splicing results in several transcript variants encoding different isoforms
ABclonal Technology 488 Rabbit anti-Human CD45RA
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitosis and oncogenic transformation This PTP contains an extracellular domain a single transmembrane segment and two tandem intracytoplasmic catalytic domains and thus is classified as a receptor type PTP This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling It functions through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling This PTP also suppresses JAK kinases and thus functions as a regulator of cytokine receptor signaling Alternatively spliced transcripts variants of this gene which encode distinct isoforms have been reported
ABclonal Technology 488 Rabbit anti-Human AGTR2
This gene encodes a G-protein coupled receptor 1 family member serving as a receptor for angiotensin II It is an integral membrane protein highly expressed in fetuses and neonates but less so in adults except in the brain adrenal medulla and atretic ovary This receptor mediates programmed cell death playing a role in developmental biology and disease pathophysiology Mutations are linked to X-linked cognitive disability SARS-CoV and SARS-CoV-2 infections downregulate ACE2 receptors triggering inflammatory lesions particularly in the lungs The angiotensin AT2 receptor is upregulated in bronchoalveolar lavage samples from COVID-19 patients suggesting its role in inflammation
ABclonal Technology 594 Rabbit anti-Human IL8
The protein encoded by this gene is interleukin-8 (IL-8) a major mediator of inflammation and a member of the CXC chemokine family IL-8 is secreted by macrophages neutrophils eosinophils T lymphocytes epithelial cells and fibroblasts guiding neutrophils to infection sites It is rapidly induced by bacterial and viral products and contributes to the proinflammatory cascade playing a role in systemic inflammatory response syndrome (SIRS) IL-8 is involved in conditions like bronchiolitis cystic fibrosis coronary artery disease and endothelial dysfunction It also promotes tumor migration invasion angiogenesis and metastasis IL-8 binds to its receptor (CXCR2) increasing blood vessel permeability Elevated IL-8 levels correlate with worsened disease outcomes including sepsis This gene is part of a CXC chemokine cluster on chromosome 4q
ABclonal Technology 450 Rabbit anti-Human Ki67
Enables protein C-terminus binding activity Involved in regulation of chromosome segregation and regulation of mitotic nuclear division Located in chromosome nuclear body and nucleolus Colocalizes with condensed chromosome Implicated in Crohn s disease breast cancer human immunodeficiency virus infectious disease and pancreatic cancer Biomarker of several diseases including Barrett s esophagus autoimmune disease of musculoskeletal system (multiple) endocrine gland cancer (multiple) gastrointestinal system cancer (multiple) and interstitial cystitis
ABclonal Technology 450 Rabbit anti-Human CD22
Predicted to enable CD4 receptor binding activity protein phosphatase binding activity and sialic acid binding activity Involved in B cell activation negative regulation of B cell receptor signaling pathway and regulation of endocytosis Located in early endosome and recycling endosome